纳米颗粒通过逃避肺而引起血管风险

一项新研究表明，[新德里]吸入的纳米颗粒可以越过肺部，进入血液，并积聚在血管和其他容易患心血管疾病的身体部位。

People around the world are constantly exposed to nanoparticles mostly emitted by vehicle exhaust, but the risks are greater in crowded Asian cities, which are seeing a dramatic rise in the number of vehicles on the roads.

In the study — the结果于4月26日发布ACS纳米—结果表明healthy volunteers exposed to gold nanoparticles retained them in the body for as long as three months. Experiments on mice also reveal that nanoparticles accumulate in the liver and blood vessels.

作者写道，到目前为止，人类研究的结果一直不一致。但是有证据表明纳米颗粒通过逃避肺进入血液循环，“提供了一种直接的机制，可以解释环境纳米颗粒与心血管之间的联系beplay足球体育的微博疾病”。他们补充说，这也对管理工程纳米颗粒的潜在风险有影响。

The link between environmental nanoparticles and cardiovascular disease could be explained by gold particles detected in surgical specimens of diseased carotid artery from patients at risk of stroke and at sites of vascular inflammation, according to the study.

“一个全面的毒理学检测需求to be performed with all new nanomaterials, especially with attention to the cardiovascular system.”

爱丁堡大学马克·米勒

尽管它是用金纳米颗粒进行的，但研究人员认为结果可以扩展到车辆排气中的纳米颗粒。

英国爱丁堡大学高级研究科学家Mark Miller和该研究的相应作者说：“这是我们目前正在研究的进一步研究。”

环境空气中的纳米颗粒来自天然和人工来源，但车辆是苏尔里大学空气质量与健康教授Prashant Kumar的主要罪魁祸首。

他说：“在繁忙的道路等污染环境中，他们贡献了总数的90％。”beplay足球体育的微博

In Europe, tighter emission norms have reduced the number of nanoparticles emitted by diesel engines. However, the situation is different in developing Asia Pacific countries where older vehicles are still widely used, and the burning of solid fuels for cooking already adds to particulate matter in ambient air.

Nanotechnology is expected to touch human lives in many ways, but the risks associated with newengineered nanomaterialsare poorly understood.

米勒说：“需要对所有新纳米材料进行全面的毒理学筛查，尤其是对心血管系统的关注。”

This piece was produced by SciDev.Net’s Asia & Pacific desk.